Is gene editing now precise enough to modify a single letter of DNA?
Gene editing has the power to completely reshape our world. It promises everything from fixing the genetic faults that lead to disease, to destroying disease-causing microbes, to improving the nutrition of the foods we eat and even resurrecting extinct species like the wooly mammoth — all largely thanks to the genetic editing tool CRISPR, which has both popularized this work and made it possible. Now, researchers in Japan have developed a new gene editing technique that uses CRISPR alongside a DNA repair system to modify a single DNA base in the human genome, with what the team’s press release calls “absolute precision.”
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